Giamarellou Eleni

Giamarellou Eleni Internist - Infectious Diseases

Director of 1st Internal Medicine & Infectious Diseases Department HYGEIA Hospital

Education & Academic Qualifications

  • Alexandra Univarsity Hospital, Athens, Greece – Resident In Internal Medicine 1966-1969
  • 1st Department Of Propedeutic Medicine, Laikon ‘General’ Hospital, Athens University School Of Medicine, Athens, Greece.
  • Chief Resident 1969-1973
  • University Scientific Assistant 1973-1975
  • Scientific Supervisor Of The Department 1975-1982
  • Head, Infectious Diseases And Antimicrobial Chemotherapy Research Laboratory (Founder) 1975-1997
  • Lecturer Of Internal Medicine 1982-1983
  • Assistant Professor Of Internal Medicine 1983-1991
  • Associate Professor Of Internal Medicine 1991-1996
  • Professor Of Internal Medicine 1997- 2009
  • 4th Department Of Internal Medicine, Sismanoglion General Hospital, Athens (Marousi), Greece.
  • Professor And Head Of The Department 1998-2003
  • Head Infectious Diseases And Antimicrobial Chemotherapy Research Laboratory 1997 – 2003
  • 4th Department Of Internal Medicine, “Attikon” University General Hospital, Athens (Chaidari), Greece
  • Professor And Head Of Department 2003-31/08/2009
  • Head Infectious Diseases And Antimicrobial Chemotherapy Research Laboratory 2003- 31/08/2009
  • Emeritus Professor Of Internal Medicine – Athens University Medical School
  • November 2009-Present
  • 6th Department Of Internal Medicine,Hygeia General Hospital, Athens (Marousi), Greece
  • Head Of Department 2010-Present
  • Head Of Infectious Diseases Research Laboratory 2011-Present


  • Md (Medical Doctor): June 1966, Faculty Of Medicine, University Of Athens, Greece.
  • Doctoral Thesis: May 1970, Alexandra University Hospital, University Of Athens Medical School, Greece.
  • Boards In Internal Medicine: October 1970, Greek Ministry Of Health
  • Abraham Lincoln School Of Medicine, University Of Illinois, Chicago, Usa. Research Fellow In Infectious Diseases 1973-1974. (Head: Professor George G. Jackson)
  • Mayo Clinic, Rochester, N .York; Usa. Postdoctoral Trainee In Anaerobic Bacteriology, November 1974.
  • Memorial Sloan Kettering Institute, New York, Usa. Postdoctoral Trainee In Immunocompromised Host Infections, September 1974 And September 1981.
  • Infectious Diseases Subspecialty: 1996, Greek Ministry Of Health (First Establishment For Greece In 1996)


Doctoral thesis

  • Ph.D. (Antimicrobial Chemotherapy): May 1981, 1st Department of Propaedeutic Medicine, University of Athens Medical School, Greece.

Fellowship in Societies, Membership in Journal Editorial Committees

  • Hellenic Society of Internal Medicine.

  • The Athens Medical Society.

  • Hellenic Society of Chemotherapy (General Secretary 1982-1997 and Presi-dent of the Executive Committee 1998-present).

  • Hellenic Association for the Study and Control of AIDS.

  • Hellenic Society for Infectious Diseases (Founder and Past President 1993- 1996).

  • Hellenic Society for Medical Education.

  • Association “Friends of Institute Pasteur”.

  • Mediterranean Society of Chemotherapy

  • International Society of Chemotherapy (Board member 1989-1993). Honorary Member since 2011

  • British Society for Antimicrobial Chemotherapy

  • European Society for Clinical Microbiology and Infectious Diseases

  • Infectious Diseases Society of America (FIDSA)

  • Hospital Infection Society. (UK)

  • E. O. R. T. C.: European Organization for Research on Treatment of Cancer.

  • ISGAR: International Society Group on Antimicrobial Resistance.

  • International Immunocompromised Host Society.

  • International Society for Anaerobic Bacteria.

  • Alliance for the Prudent of Use of Antibiotics (APUA).

  • New York Academy of Sciences.

  • Surgical Infection Society Europe.

  • F. E. S. C. I. (Federation of European Society of Chemotherapy and Infec-tious Diseases) (President 2003-2007).

  • ICE (International Collaboration Endocarditis): Duke University, Durham, USA.

  • General Secretary of the Executive Board of “Amphiaraion Foundation of Chemotherapeutic Studies” (1985- present). The foundation was established in Athens, Greece, after the 4th Mediterranean Congress of Chemotherapy that took place in Rhodes in 1984. The main aim of the Foundation is the education of young physicians in Antimicrobial Chemotherapy as well as the administra-tion of relevant fellowships in Greece and abroad.

  • Founder and Honorary Member of the ESCMID Study Group on “Infection in the Critically Ill Patients” (2011-present)

Editorial Boards:

AD-HOC REVIEWER for peer-reviewed international journals

  • Clinical Infectious Diseases (USA).

  • Infectious Disease Practice for the Clinician (USA).

  • Clinical Microbiology and Infection. (ESCMID- Switzerland)

  • Infectious Diseases in Clinical Practice (USA).

  • European Journal of Clinical in Clinical Microbiology and Infectious Diseases

  • Drugs (New Zealand).

  • Drug Investigation.

  • Journal of Chemotherapy

  • Revista Espaniola di Quimioterapia (Spain).

  • American Journal of Clinical Dermatology. (USA)

  • Lancet Infections Diseases. (UK)

  • Journal of infection (UK).

  • Journal of Antimicrobial Chemotherapy (UK).

  • Antimicrobial Agents and Chemotherapy (USA).

  • Expert Opinion on Pharmacotherapy.

  • Journal of Pediatric Infectious Diseases (USA).

  • International Journal Antimicrobial Agents (UK).

  • Intensive Care Medicine.

  • Expert Opinion on Investigational Drugs.

  • The Lancet

  • Eurosurveillance

  • Minerva Anestesiologica

  • Expert Review of Anti-infective Therapy

  • The Open Emergency Medicine Journal

  • The Medical Letter

  • Scandinavian Journal of Infectious Disease

  • Saudi Journal for Health Sciences

  • PLoS ONE

  • Respiration (International Journal of Thoracic Medicine)


Work Experience

Education Experience:

  • Physical Examination, Medical Diagnosis and Treatment in Internal Medicine, Infectious Diseases and Antimicrobial Chemotherapy (students of 7th, 8th, 11th and 12th Semester, University of Athens Medical School):1970 – 2010.

  • Elective course “Infection and Antimicrobial Chemotherapy” from 1987-2009 (students of 8th – 12th Semester of University of Athens Medical School).Teaching and organization responsibility.

  • Establishment of Annual Interactive Courses on “Rational Use of Antibiotics” for all last year students of Athens Medical School: 2006 – present (founder, organizer and teacher).

  • Postgraduate courses and lectures on subjects of Antimicrobial Chemotherapy and Infectious Diseases at University Medical Schools in Greece and abroad, as well as hospitals ,scientific societies and associations across the country and internationally.

  • 2010- present: Organizer and teacher in 19 two-day courses on Rational Anti-microbial Therapy for Community-acquired infections. The courses across the country have been attended by more than 2500 GPs. The courses are under the auspices of the Hellenic Ministry of Health, the ECDC and HCDCP (Hel-lenic Center for Disease Control and Prevention)

  • Organizer and teacher of 2 or 3-day Seminars in cycles on Rational Antimi-crobial Therapy for Hospital physicians (clinicians) in Athens and hospitals of the Providence in co-operation with HCDCP.


Clinical & Research Interest

  • In vitro activity of new antibacterial agents

  • In vivo evaluation of antibiotics (clinical trials)

  • Pharmacokinetic and pharmacodynamic studies of newer antibiotics;

  • Resistance surveillance studies

  • Epidemiology of resistance

  • Molecular investigation of antibiotic resistance mechanisms

  • Experimental animal models (experimental endocarditis; experimental perito-nitis; experimental osteomyelitis)

  • Nosocomial infections

  • Antibiotic stewardship

  • Neutropenic host infections

  • Infection control (hand hygiene in particular)

  • ICU infections

  • Clinical evaluation and PK/PD of Colistin, Tigecycline and Fosfomycin

  • Epidemiology of Gram-negative bacteria producing Carbepenemases

  • Therapy of XDR and PDR Gram-negative infections


Recent Publications

  • >500 publications in medical journals (Peer-review)

  • Citations : >7000 times

  • h index : 48 (Scopus)

  • >600 abstracts in International Conferences/Congresses and scientific meet-ings and112 publications in Greek medical journals

  • 55 Books: 42 chapters in 20 international medical books on Antimicrobial Chemotherapy and Infectious Diseases and 130 chapters in 34 Greek medical books, as well as Editor in 4 Greek books

  • 155 Doctoral Thesis (Athens University Medical School)

  • More than 1000 abstracts presented at conferences/congresses and scientific meetings in Greece

  • Participation in 305 Greek and international conferences with lectures. Specif-ically, 121 lectures and talks internationally and 184 lectures in Greece

  • 33 studies have been awarded in Greece and internationally

  • Nine (9) new genes of antimicrobial resistance have been submitted at the In-ternational gene Bank

Recent Publications (since 2010):

  • Nationwide surveillance of resistance rates of Staphylococcus aureus clinical isolates from Greek hospitals, 2012-2013.

  • Souli M, Karaiskos I, Galani L, Maraki S, Perivolioti E, Argyropoulou A, Charissi-adou A, Zachariadou L, Tsiplakou S, Papaioannou V, Tsorlini H, Katsifa H, Baka V, Pantazi P, Paschali A, Kyratsa A, Trikka-Graphakos E, Giannopoulou P, Vogiatzakis E, Moraitou H, Papadogeorgaki H, Avgerinou H, Panagea T, Panta-zatou A, Petinaki E, Stamatopoulou G, Toutouza M, Karatzoglou I, Kontopoulou K, Orfanidou M, Karantani I, Fytas P, Tzanetou K, Platsouka E, Kazila P, Chli A, Statiri N, Giamarellou H. Infect Dis (Lond). 2015;4:1-6

  • Promoting prudent use of antibiotics: the experience from a multifaceted regional campaign in Greece. Plachouras D, Antoniadou A, Giannitsioti E, Galani L, Katsarolis I, Kavatha D, Koukos G, Panagopoulos P, Papadopoulos A, Poulakou G, Sakka V, Souli M, Sybardi S, Tsiodras S, Kanellakopoulou K, Giamarellou H. BMC Public Health. 2014;14:866

  • Multidrug-resistant and extensively drug-resistant Gram-negative pathogens: current and emerging therapeutic approaches. Karaiskos I, Giamarellou H.Expert Opin Pharmacother. 2014;15(10):1351-70.

  • Outcomes of critically ill intensive care unit patients treated with fosfomycin for infections due to pandrug-resistant and extensively drug-resistant car-bapenemase-producing Gram-negative bacteria.Pontikis K, Karaiskos I, Bastani S, Dimopoulos G, Kalogirou M, Katsiari M, Oikonomou A, Poulakou G, Roilides E, Giamarellou H.Int J Antimicrob Agents. 2014;43(1):52-9.

  • Effectiveness of a double-carbapenem regimen for infections in humans due to carbapenemase-producing pandrug-resistant Klebsiella pneumoniae.Giamarellou H, Galani L, Baziaka F, Karaiskos I.Antimicrob Agents Chemother. 2013;57(5):2388-90

  • Pharmacokinetic and pharmacodynamic evaluation of tigecycline.Expert Opin Drug Metab Toxicol. 2011;7(11):1459-70.

  • Colonization and infection by colistin-resistant Gram-negative bacteria in a cohort of critically ill patients.Kontopidou F, Plachouras D, Papadomichelakis E, Koukos G, Galani I, Poulakou G, Dimopoulos G, Antoniadou A, Armaganidis A, Giamarellou H. Clin Microbiol Infect. 2011;17(11):E9-E11.

  • When and how to cover for resistant gram-negative bacilli in severe sepsis and septic shock.

  • Hanberger H, Giske CG, Giamarellou H. Curr Infect Dis Rep. 2011;13(5):416-25.

  • Metallo-β-lactamases: a last frontier for β-lactams?Cornaglia G, Giamarellou H, Rossolini GM.

  • Lancet Infect Dis. 2011;11(5):381-93.

  • Multidrug-resistant Gram-negative bacteria: how to treat and for how long.Giamarellou H.Int J Antimicrob Agents. 2010;36 Suppl 2:S50-4.