Melakopoulos Ioannis

Melakopoulos Ioannis Maxillofacial

Attending Physician, Oral & Maxillofacial Surgery Department HYGEIA Hospital

Education & Academic Qualifications

  • DipDS Athens 1993
  • Doctorate Diploma in Medecine (Ph D) 1999


Doctoral thesis

  • 1999 I. Melakopoulos: “Changes of serum and tissues of selected macrolides (azithromycin, clarithromycin and dirythromycin) levels following chloropromazine administration in rats.” Medical School ATHENS

Fellowship in Societies, Membership in Journal Editorial Committees

  • President of the “Stomatological Society of Greece”

  • Member of the European Association for Cranio-Maxillofacial Surgery

  • Member of the Hellenic Association for Oral & Maxillofacial Surgery

Editorial Boards:

AD-HOC REVIEWER for peer-reviewed international journals

  • Journal of Cranio-Maxillofacial Surgery


Work Experience

  • 2012-today Consultant in OMS

  • 2007-2008 Clinical attachment in OMS clinic in Chelsea & Westminster Hospital , London, to Mr Henri Thuau.

  • 2004-2011 Working as a consultant in OMS

Education Experience:

  • 2003 Clinical attachment in OMS clinic in Central Middlessex Hospital , London to Mr Henri Thuau.

  • 2000-2003 SPR. in Oral and Maxillofacial Surgery (OMS), department in Ippokration General Hospital, , Athens, to As. Prof. Maria Bosinakou. This post is recognised for the Oral and Maxillofacial Surgery training,.

  • 1999 to 2000 S.H.O. in the Department of General Surgery at Tripoli‘s General Hospital as part of OMS training post.

  • 1993-1998 Clinical Assistant in the department of Oral and Maxillofacial surgery to Prof A. Patrikiou, as well as in Oral and Maxillofacial Surgery Clinic of Children Hospital “P&A Kyriakou to Prof P. Anastasiadis.


Clinical & Research Interest

Clinical Interest:

  • Facial deformities

  • Orthognathic Surgery

  • Medical related Osteonecrosis of the Jaws

  • Advanced Implant Surgery

Research Interest:

  • Medical related Osteonecrosis of the Jaws

  • Clinical Pharmacology

  • Oral and Maxillofacial infections


Recent Publications

  • Melea PI, Melakopoulos I, Kastritis E, Tesseromatis C, Margaritis V, Dimopoulos MA, Terpos E. Conservative treatment of bisphosphonate-related osteonecrosis of the jaw in multiple myeloma patients. Int J Dent. 2014;2014:427273. doi: χ10.1155/2014/427273. Epub 2014 Jun 17. PubMed PMID: 25045353; PubMed Central PMCID: PMC4087254.

  • Poulias E, Melakopoulos I, Tosios K. Metastatic breast carcinoma in the mandible presenting as a periodontal abscess: a case report. J Med Case Rep. 2011 Jul 1;5:265. doi: 10.1186/1752-1947-5-265. PubMed PMID: 21722359; PubMed Central

  • PMCID: PMC3151228.

  • Nikitakis NG, Brooks JK, Melakopoulos I, Younis RH, Scheper MA, Pitts MA, Al-Mubarak H, Sklavounou A. Lateral periodontal cysts arising in periapical sites: a report of two cases. J Endod. 2010 Oct;36(10):1707-11. doi: 10.1016/j.joen.2010.06.015. Epub 2010 Aug 11. PubMed PMID: 20850683. 

  • Dimopoulos MA, Kastritis E, Bamia C, Melakopoulos I, Gika D, Roussou M, Migkou M, Eleftherakis-Papaiakovou E, Christoulas D, Terpos E, Bamias A. Reduction of osteonecrosis of the jaw (ONJ) after implementation of preventive measures in patients with multiple myeloma treated with zoledronic acid. Ann Oncol. 2009 Jan;20(1):117-20. doi: 10.1093/annonc/mdn554. Epub 2008 Aug 9. PubMed PMID: 18689864.

  • Melakopoulos I, Karageorgopoulos DE, Christodoulou C, Skarlos DV, Falagas ME.  Tooth and consequences. Am J Med. 2008 Jul;121(7):577-9. doi: 10.1016/j.amjmed.2007.12.001. PubMed PMID: 18589052.

  • Dimopoulos MA, Kastritis E, Anagnostopoulos A, Melakopoulos I, Gika D, Moulopoulos LA, Bamia C, Terpos E, Tsionos K, Bamias A. Osteonecrosis of the jaw  in patients with multiple myeloma treated with bisphosphonates: evidence of increased risk after treatment with zoledronic acid. Haematologica. 2006 Jul;91(7):968-71. Epub 2006 Jun 1. PubMed PMID: 16757414.

  • Bamias A, Kastritis E, Bamia C, Moulopoulos LA, Melakopoulos I, Bozas G, Koutsoukou V, Gika D, Anagnostopoulos A, Papadimitriou C, Terpos E, Dimopoulos MA. Osteonecrosis of the jaw in cancer after treatment with bisphosphonates:

  • incidence and risk factors. J Clin Oncol. 2005 Dec 1;23(34):8580-7. PubMed PMID:  16314620.

  • Tsivou E, Melakopoulos I, Kotsiou A, Anagnostopoulou S, Tesseromatis C. Alterations in cefalosporin levels in the serum and mandible of hyperlipaedemic rats after co-administration of ibuprofen. Eur J Drug Metab Pharmacokinet. 2005 Jul-Sep;30(3):171-4. PubMed PMID: 16250253.