Education & Academic Qualifications


  • 08/01/03-07/01/04: Assistant Professor of Pediatrics, University of Arkansas for Medical Sciences. 
  • 08/12/2013-08/1/2016: Assistant Professor of Pediatrics University of Missouri in Kansas City.
  • 08/01/2016-now: Associate Professor of Pediatrics, University of Missouri in Kansas City.


  • 1977-1983: Aristotelian University of Thessaloniki
  • 06/24/85-30/06/88: Resident in Pediatrics, St Louis Children’s Hospital at Washington University Medical Center, St Louis, Missouri, USA
  • 07/01/88-30/06/91: Fellow in Pediatric Cardiology, Duke University Medical Center, Durham, N. Carolina, USA
  • 07/01/91-30/07/92: Fellow in Cardiac Pathology, Children’s Hospital, Harvard Medical School, Boston, USA
  • 09/01/95-08/31/96: Fellow in Pediatric Cardiac Electrophysiology, Duke University Medical Center, Durham, USA

PhD/ Thesis

  • 2004: University of Patras, Greece: “Definitive treatment of supraventricular tachycardia in children with radiofrequency current.”

Board Certification

  • General Pediatrics certificate # Γ2/24980/05/10/90, Thessaloniki, Greece

  • Diplomate, American Board of Pediatrics: 02/06/89

  • Diplomate, American Board of Pediatrics and Sub-Board of Pediatric Cardiology, 11/10/91, Recertified 6/2014

  • International Board of Heart Rhythm Examiners: Certification in Clinical Electrophysiology, Pediatric Electrophysiology, December 2014

  • International Board of Heart Rhythm Examiners: Certification Cardiac Rhythm Device Specialist, August 2015

Editorial Boards

AD-HOC REVIEWER for peer-reviewed international journals: Circulation, PACE, Europace

Professional Experience

  • 09/01/92-11/30/93: Pediatric Cardiologist, Athens Medical Center, Athens, Greece.

  • 12/01/93-12/31/97: Attending Pediatric Cardiologist, Onassis Cardiac Surgery Center, Athens, Greece. From 09/01/95-08/31/96: Leave of absence for training in Pediatric Electrophysiology.

  • 01/01/98-07/30/03: Associate Director, Division of Pediatric Cardiology, Onassis Cardiac Surgery Center, Athens, Greece

  • 08/01/03-07/01/04: Director, Pediatric Electrophysiology, Division of Cardiology, Arkansas Children’s Hospital, Little Rock, Arkansas, USA

  • 07/01/04-12/31/2007: Associate Director, Division of Pediatric Cardiology and Director of Pediatric Electrophysiology, Onassis Cardiac Surgery Center, Athens, Greece

  • 1/1/2008-7/30/2013: Director, Pediatric Cardiology and Electrophysiology, Mitera Children’s Hospital, Athens, Greece

  • 08/12/2013-now: Director of Electrophysiology, Division of Pediatric Cardiology, Department of Pediatrics, Children’s Mercy Hospital, Kansas City, Missouri, USA.

  • Education Experience: Invited Speaker and Chair in multiple national and international meetings

Clinical and Research Interest

Clinical Interest

  • Pediatric electrophysiology: transcatheter ablation of supraventricular and ventricular arrhythmias (using both radiofrequency and cryoablation) with the use of 3D mapping non-fluoroscopic techniques; pacemaker and defibrillator implantation and follow-up; non-invasive electrophysiology testing; tilt-table testing; investigation and follow-up of genetic arrhythmia syndromes (Long QT, Catecholaminergic Polymorphic Ventricular Tachycardia, Brugada syndrome, Hypertrophic  and Dilated Cardiomyopathy, Arrhythmogenic Right Ventricular Cardiomyopathy) .

  • General Pediatric Cardiology: Clinical cardiology, echocardiography, cardiac catheterization in infants, children, adolescents and adults with congenital heart disease.

Research Interests

  • Pediatric Cardiology: New clinical and diagnostic findings in Congenital Heart Disease.

  • Cardiac Pathology:  Clinical-pathologic correlations, with echocardiographic and angiocardiographic findings in congenital heart disease.

  • Pediatric Cardiac Electrophysiology and Pacing:

    • Effects of radiofrequency lesions on the immature myocardium.

    • Treatment of pediatric cardiac arrhythmias with radiofrequency ablation. Non-fluoroscopic imaging in pediatric catheter ablation.

    • Cryoablation in the treatment of pediatric arrhythmias.

    • Treatment of postoperative cardiac arrhythmias in patients with congenital heart disease with radiofrequency ablation.

    • Impact of the permanent ventricular pacing site on left ventricular function in children

    • Cardiac Resynchronization in Children and Patients with Congenital Heart Disease.

    • New clinical and molecular genetic findings in patients with genetic arrhythmia syndromes.


Chapters in Books

1. The heart in Down syndrome: Pathologic anatomy.
R. Van Praagh, J. Papagiannis, Y. Bar-El, O. Schwint
In: Heart Disease in Persons with Down Syndrome, pp 69-111, Paul H. Brooks publisher, Baltimore 1996

2. Pulmonary atresia with intact ventricular septum: Right ventricular and coronary artery anatomy.
R. Van Praagh, J .Papagiannis, C. Hanioti, M. Kiaffas.
In: Pediatric Cardiology Updates, pp 45-49, H. C. Lue editor, Springer-Verlag, Tokyo 1997

3. Acute treatment of tachyarrhythmias.
A. Winslow, J. Papagiannis, R. Kanter. In: Clinical Pediatric Arrhythmias 2nd edition, pp 149-163, P.C. Gillette and A. Garson editors, W.B. Saunders Company, Philadelphia, 1999

4. Tumors of the heart
J. Papagiannis. Cardiologic Therapeutics. D. Cokkinos, G. Parisianos Publisher, Athens, 2000

5. Interventional Pediatric Electrophysiology in children and adolescents. J. Papagiannis. In: the pediatric heart: Pathology-prevention-treatment, pp 157-165. C. S. Bartsokas, S. Rammos, eds.  Joined publication of the Department of Pediatrics, Aglaia Kyriakou Children’s Hospital, University of Athens, and Division of Pediatric Cardiology, Onassis Cardiac Surgery Center, Athens, 2001

6. Treatment of Supraventricular Tachycardias in Children with     Radiofrequency Current. J. Papagiannis, Doctoral Thesis University Studio Press, Thessaloniki, 2005

Recent Publications

  • Atrioventricular Nodal Reentrant Tachycardia in Patients with Congenital Heart Disease: Outcome after Catheter Ablation. Papagiannis J, Beissel DJ, Krause U, Cabrera M, Telishevska M, Seslar S, Johnsrude C, Anderson C, Tisma-Dupanovic S, Connelly D, Avramidis D, Carter C, Kornyei L, Law I, Von Bergen N, Janusek J, Silva J, Rosenthal E, Willcox M, Kubus P, Hessling G, Paul T; Pediatric and Congenital Electrophysiology Society. Circ Arrhythm Electrophysiol. 2017 Jul;10(7).

  • PACES/HRS expert consensus statement on the use of catheter ablation in children and patients with congenital heart disease: Developed in partnership with the Pediatric and Congenital Electrophysiology Society (PACES) and the Heart Rhythm Society (HRS). Endorsed by the governing bodies of PACES, HRS, the American Academy of Pediatrics (AAP), the American Heart Association (AHA), and the Association for European Pediatric and Congenital Cardiology (AEPC).
    Philip Saul J, Kanter RJ; WRITING COMMITTEE, Abrams D, Asirvatham S, Bar-Cohen Y, Blaufox AD, Cannon B, Clark J, Dick M, Freter A, Kertesz NJ, Kirsh JA, Kugler J, LaPage M, McGowan FX, Miyake CY, Nathan A, Papagiannis J, Paul T, Pflaumer A, Skanes AC, Stevenson WG, Von Bergen N, Zimmerman F.
    Heart Rhythm. 2016 Jun;13(6):e251-89.

  • Management of paediatric arrhythmias in Europe.
    Happonen JM, Blom N, Celiker A, Drago F, Hebe J, Janousek J, Kornyei L, Kriebel T,Papagiannis J, Paul T, Pfammatter JP, Rosenthal E, Tuzcu V.

    Europace. 2015 Dec;17(12):1879.

  • Permanent junctional reciprocating tachycardia in children: a multicenter experience.

    Kang KT, Potts JE, Radbill AE, La Page MJ, Papagiannis J, Garnreiter JM, Kubus P, Kantoch MJ, Von Bergen NH, Fournier A, Côté JM, Paul T, Anderson CC, Cannon BC, Miyake CY, Blaufox AD, Etheridge SP, Sanatani S.

    Heart Rhythm. 2014 Aug;11(8):1426-32.

  • Transcatheter valve-in-valve implantation in the tricuspid position.
    Tzifa A, Momenah T, Al Sahari A, Al Khalaf K, Papagiannis J, Qureshi SA.

    EuroIntervention. 2014 Dec;10(8):995-9.

  • Cryoablation of atrioventricular nodal reentrant tachycardia in children and adolescents: improved long-term outcomes with increasing experience.

    Cokkinakis C, Avramidis D, Alexopoulos C, Kirvassilis G, Papagiannis J.

    Hellenic J Cardiol. 2013 May-Jun;54(3):186-91.

  • Calmodulin mutations associated with recurrent cardiac arrest in infants.
    Crotti L, Johnson CN, Graf E, De Ferrari GM, Cuneo BF, Ovadia M, Papagiannis J, Feldkamp MD, Rathi SG, Kunic JD, Pedrazzini M, Wieland T, Lichtner P, Beckmann BM, Clark T, Shaffer C, Benson DW, Kääb S, Meitinger T, Strom TM, Chazin WJ, Schwartz PJ, George AL Jr.

    Circulation. 2013 Mar 5;127(9):1009-17.

  • Permanent cardiac pacing in children: choosing the optimal pacing site: a multicenter study.

    Janoušek J, van Geldorp IE, Krupičková S, Rosenthal E, Nugent K, Tomaske M, Früh A, Elders J, Hiippala A, Kerst G, Gebauer RA, Kubuš P, Frias P, Gabbarini F, Clur SA, Nagel B, Ganame J, Papagiannis J, Marek J, Tisma-Dupanovic S, Tsao S, Nürnberg JH, Wren C, Friedberg M, de Guillebon M, Volaufova J, Prinzen FW, Delhaas T; Working Group for Cardiac Dysrhythmias and Electrophysiology of the Association for European Pediatric Cardiology.

    Circulation. 2013 Feb 5;127(5):613-23

  • Impact of the permanent ventricular pacing site on left ventricular function in children: a retrospective multicentre survey.

    van Geldorp IE, Delhaas T, Gebauer RA, Frias P, Tomaske M, Friedberg MK, Tisma-Dupanovic S, Elders J, Früh A, Gabbarini F, Kubus P, Illikova V, Tsao S, Blank AC, Hiippala A, Sluysmans T, Karpawich P, Clur SA, Ganame X, Collins KK, Dann G, Thambo JB, Trigo C, Nagel B, Papagiannis J, Rackowitz A, Marek J, Nürnberg JH, Vanagt WY, Prinzen FW, Janousek J; Working Group for Cardiac Dysrhythmias and Electrophysiology of the Association for European Paediatric Cardiology.

    Heart. 2011 Dec;97(24):2051-5.

  • Radiofrequency ablation of accessory pathways in children and congenital heart disease patients: impact of a nonfluoroscopic navigation system.

    Papagiannis J, Avramidis D, Alexopoulos C, Kirvassilis G.

    Pacing Clin Electrophysiol. 2011 Oct;34(10):1288-396.

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