Paraskevi Fitili

Paraskevi Fitili Gastroenterologist

Assistant, Gastroenterology Clinic

Education & Academic Qualifications

  • 2000 Graduate, Medical School of the National and Kapodestrian University of Athens, Greece
  • 2008 PhD in Medicine, University of Thessaly, Greece

PhD Thesis

«Genetical multivariance of the hepatitis C virus (HCV): Crossgenotype analysis of the  NS3-1073 HCV epitope

  • 05/2002-01/2005 Department of Medicine & Research Lab, University of Thessaly, Prof. G.N. Dalekos
  • 02/2005-07/2008 Laboratory of viral Immunology, Department of Gastroenterology Hepatology and Endocrinology, Medical School of Hannover (MHH), Prof. Dr. med. H. Wedemeyer, Prof. Dr. med M.P. Manns

Professional Experience

  • 10/2000-01/2002 Rural doctor, Sykourion, Thessalia, Greece
  • 08/2002-05/2014 Training in Internal Medicine, “Amalia Fleming” Hospital, Athens
  • 01/2006-06/2016 Specialization in Internal Medicine, Gastroenterology and Hepatology in the Department of Gastroenterology, Hepatology and Endocrinology of the Medical School of Hannover (MHH), Head Prof. Dr. med. M.P. Manns .
  • 03/2012 Consultant for Internal Medicine, Medical Board of Lower Saxony
  • 04/2015 Consultant for Gastroenterology and Hepatology, Medical Board of Lower Saxony
  • 09/2016-today Consultant Gastroenterologist of the Gastroenterology Clinic ‘Mitera General Maternity and Paediatrics Clinic’

Clinical and Research Interest

  • Clinical Interest:  Viral hepatitis, liver cirrhosis, Colon cancer, Colonic polyps, Barrett’s esophagus, gastroesophageal reflux disease, celiac disease, Irritable bowel syndrom
  • Research Interest:  Development of biomarkers in different stages of chronic hepatitis B and C for the optimised guidance of the antiviral therapy.


04-07/2005  Scholarship of the German Association for Academic Scholarships (Deutscher Akademischer Austausch Dienst, D.A.A.D.)

Society Member

  • Member of the Greek Gastroenterology Association
  • Member of the European Association of the Study of the Liver

Recent Publications

  • Zhang S, Bakshi RK, Suneetha PV, Fytili P, Antunes DA, Vieira GF, Jacobs R, Klade CS, Manns MP, Kraft AR, Wedemeyer H, Schlaphoff V, Cornberg M. Frequency, Private Specificity, and Cross-Reactivity of Preexisting Hepa-titis C Virus (HCV)-Specific CD8+ T Cells in HCV-Seronegative Individuals: Implications for Vaccine Responses. J Virol. 2015 Aug;89(16):8304-17.
  • Gronert Álvarez A, Fytili P, Suneetha PV, Kraft AR, Brauner C, Schlue J, Krech T, Lehner F, Meyer-Heithuis C, Jaeckel E, Klempnauer J, Manns MP, Cornberg M, Wedemeyer H. Comprehensive phenotyping of regulatory T cells after liver transplantation. Liver Transpl. 2015 Mar;21(3):381-95.
  • Brauner C, Lankisch TO, Fytili P, Jaroszewicz J, Lehner F, Barg-Hock H, Klempnauer J, Jaeckel E, Manns MP, Wedemeyer H, Negm AA. Clinical val-ue and safety of liver biopsies in patients transplanted for hepatitis C virus-related end-stage liver disease. Transpl Infect Dis. 2014 Dec;16(6):958-67.
  • Suneetha PV, Pischke S, Schlaphoff V, Grabowski J, Fytili P, Gronert A, Bremer B, Markova A, Jaroszewicz J, Bara C, Manns MP, Cornberg M, Wedemeyer H. Hepatitis E virus (HEV)-specific T-cell responses are associ-ated with control of HEV infection. Hepatology. 2012 Mar;55(3):695-708.
  • Stegmann KA, Björkström NK, Veber H, Ciesek S, Riese P, Wiegand J, Hadem J, Suneetha PV, Jaroszewicz J, Wang C, Schlaphoff V, Fytili P, Cornberg M, Manns MP, Geffers R, Pietschmann T, Guzmán CA, Ljunggren HG, Wedemeyer H. Interferon-alpha-induced TRAIL on natural killer cells is associated with control of hepatitis C virus infection. Gastroenterology. 2010 May;138(5):1885-97.
  • Wang C, Heim A, Schlaphoff V, Suneetha PV, Stegmann KA, Jiang H, Krue-ger M, Fytili P, Schulz T, Cornberg M, Kandolf R, Manns MP, Bock CT, Wedemeyer H. Intrahepatic long-term persistence of parvovirus B19 and its role in chronic viral hepatitis. J Med Virol. 2009 Dec;81(12):2079-88.
  • Suneetha PV, Schlaphoff V, Wang C, Stegmann KA, Fytili P, Sarin SK, Manns MP, Cornberg M, Wedemeyer H. Effect of peptide pools on effector functions of antigen-specific CD8+ T cells. J Immunol Methods. 2009 Mar 15;342(1-2):33-48.
  • Fytili P, Dalekos GN, Schlaphoff V, Suneetha PV, Sarrazin C, Zauner W, Zachou K, Berg T, Manns MP, Klade CS, Cornberg M, Wedemeyer H. Cross-genotype-reactivity of the immunodominant HCV CD8 T-cell epitope NS3-1073. Vaccine. 2008 Jul 23;26(31):3818-26.
  • Fytili P, Tiemann C, Wang C, Schulz S, Schaffer S, Manns MP, Wedemeyer H. Frequency of very low HCV viremia detected by a highly sensitive HCV-RNA assay. J Clin Virol. 2007 Aug;39(4):308-11.
  • Fytili P, Ciesek S, Manns MP, Wedemeyer H, Neipp M, Helfritz F, Klemp-nauer J, Bara C, Haverich A. Anti-HBc seroconversion after transplantation of anti-HBc positive nonliver organs to anti-HBc negative recipients. Trans-plantation. 2006 Mar 15;81(5):808-9.