|Mitera|||||General Clinic|||||Maternity / Gynecological Clinic|||||MITERA Children’s Hospital|
The new Hereditary Hemolytic Anemia Department established within MITERA Children’s Hospital can effectively contribute towards safe diagnosis of anemias, especially in childhood.
Hemoglobinopathies are inherited hemoglobin disorders which can be split into two major categories:
Thalassemias and drepanocytic anemias are the most commonly encountered single-gene blood disorders worldwide, so diagnosis and treatment of patients constitutes a major public health issue. A child or adult may be a carrier of one of the syndromes (heterozygous) or may be affected by them (homozygous) due to the combination of two carriers. Carriers (heterozygous) are not affected. Only homozygous individuals are affected.
The clinical condition of homozygous patients is quite diverse. The gravity of the clinical symptoms greatly relates to the genetic disorder. There are patients with mild clinical condition, while a large proportion of patients may demonstrate severe clinical condition and may require systematic treatment from infancy, through blood transfusions.
The main problem in these patients is severe anemia due to decreased hemoglobin production, as well as continuous reduction of erythrocytes (red blood cells) due to hemolysis.
Around 7% of the population are carriers of various hemoglobinopathies. According to World Health Organization (WHO) statistics, approximately 500,000 new cases are diagnosed annually.
It is estimated that 8% of the population in Greece are carriers of alpha and beta thalassemias. Their distribution is heterogeneous and varies from 5% to 20% in certain areas.
In countries such as Greece, where these disorders are considered endemic, safe and reliable diagnosis is more than imperative.
A modern hemoglobinopathy diagnosis center operates within the HYGEIA Group central labs. Diagnosis of these anemias, mainly in childhood, is based on a series of general and special lab tests. The whole family often needs to be tested for safer diagnosis.
The lab tests include:
Hemoglobinopathy diagnosis is a complex process that requires evaluation of all lab findings and clinical data.
In terms of public health, prevention is the key to limiting hemoglobinopathies. This means early, accurate and reliable diagnosis of carriers (heterozygous), as well as proper genetic guidance to prevent the birth of affected children.
T.: +30 210 6869404, +30 210 6869563, +30 210 6869564